Journal of Biomedical Optics, May/June 2008
J. Biomed. Opt. 13, 030506 (2008) (3 pages)
©2008 Society of Photo-Optical Instrumentation Engineers. All rights reserved.
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JBO Letters
Real-time swept source optical coherence tomography imaging of the human airway using a microelectromechanical system endoscope and digital signal processor
Jianping Su,1
Jun Zhang,2
Lingfeng Yu,2
Henri G Colt,3
Matthew Brenner,2,3 and
Zhongping Chen1,2 †
1University of California, Irvine, Department of Biomedical Engineering, Irvine, California 92612
2University of California, Irvine, Beckman Laser Institute, Irvine, California 92612
3University of California, Pulmonary and Critical Care Division, Irvine Medical Center, Orange, California 92868
(Received: 19 February 2008; revised: 5 April 2008; accepted: 13 April 2008; published online: 1 July 2008)A fast-scan-rate swept laser for optical coherence tomography (OCT) is suitable to record and analyze a 3-D image volume. However, the whole OCT system speed is limited by data streaming, processing, and storage. In this case, postprocessing is a common technique. Endoscopic clinical applications prefer onsite diagnosis, which requires a real-time technique. Parallel digital signal processors were applied to stream and process data directly from a data digitizer. A real-time system with 20-kHz axial line speed, which was limited only by our swept laser scan rate, was implemented. To couple with the system speed, an endoscope based on an improved 3-D microelectromechanical motor (diameter 1.5 mm, length 9.4 mm) was developed. In vivo 3-D imaging of the human airway was demonstrated. ©2008 Society of Photo-Optical Instrumentation Engineers
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