Effects of the background optical properties on time-resolved transmittance imaging
The effects of the background optical properties on the performance of imaging of realistic absorption and scattering inhomogeneities in diffusive media were studied experimentally by varying the opti...
OCT images of human skin
The aim of this research is the investigation and improvement of the possibilities of optical coherence tomography (OCT) for evaluation and imaging of dermal lesions, such as melanoma. Single point de...
Low-coherence in-depth microscopy for biological tissue imaging: design of a real-time control system
Proc. SPIE, Vol. 3194, 198 (1998);
doi:10.1117/12.301057
Conference Date: Saturday 06 September 1997
Conference Location: San Remo, Italy
Conference Title: Photon Propagation in Tissues III
Conference Chairs: David A. Benaron, Britton Chance, Marco Ferrari
Wedescribe the design of a versatile electronic system performing alock-in detection in parallel on every pixel of a 2DCCD camera. The system is based on a multiplexed lock-in detection method that requires accurate synchronization of the camera,the excitation signal and the processing computer. This device hasbeen incorporated in an imaging setup based on the opticalcoherence tomography principle, enabling to acquire a full 2D head-onimage without scanning. The imaging experiment is implemented on amodified commercial microscope. Lateral resolution is on the order of2 micrometers , and the coherence length of the lightsource defines an axial resolution of approximately 8 micrometers .Images of onion cells a few hundred microns deep intothe sample are obtained with 100 dB sensitivity.
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