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Integrated microgiant electrorheological fluid valves for microflow cytometry

J. Micro/Nanolith. MEMS MOEMS, Vol. 8, 021103 (2009); doi:10.1117/1.3124191

Published 5 May 2009
Yun-Yang Ling and Yechi Zhang
Hong Kong University of Science and Technology, Department of Mechanical Engineering, Clear Water Bay, Hong Kong

Weijia Wen
Hong Kong University of Science and Technology, Department of Physics, Clear Water Bay, Hong Kong

Patrick Tabeling
École Supérieure de Physique et de Chimie Industrielle, Microfluidic MEMS and Nanostructures Laboratory, 10 rue Vauqueline, Paris, 75231, France

Yi-Kuen Lee
Hong Kong University of Science and Technology, Department of Mechanical Engineering, Clear Water Bay, Hong Kong
We present the fabrication and optimization of new integrated microgiant electrorheological (GER) valves for microflow cytometry. Compared to previous GER valves, new GER valves, consisting of an SU-8 layer, a PDMS membrane, and glass layers, were fabricated by 4-mask microelectromechanical systems technology and two new packaging methods. This design enabled good bonding and fluidic interconnection. The thickness of the PDMS membrane was designed such that the membrane deformation was large enough that the cytometry channel was well sealed. The interfacial stress between the PDMS and the PDMS/SU-8 as a function of vacuum plasma treatment time was investigated in detail. The switching behavior of the GER valves was also analyzed and characterized using fluorescence microscopy.

©2009 Society of Photo-Optical Instrumentation Engineers
History: Received 20 August 2008; revised 5 February 2009; accepted 17 March 2009; published 5 May 2009
DOI Link: http://dx.doi.org/10.1117/1.3124191
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KEYWORDS and PACS

Keywords
PACS
  • 87.85.gf
    Fluid mechanics and rheology (biomechanics in biomedical engineering)
  • 85.85.+j
    Micro- and nano-electromechanical systems (MEMS/NEMS) and devices
  • 47.63.-b
    Biological fluid dynamics
  • 47.61.Fg
    Flows in micro-electromechanical systems (MEMS) and nano-electromechanical systems (NEMS)
  • 47.85.Np
    Fluidics (applied)
  • 87.18.-h
    Biological complexity
  • YEAR: 2009

JOURNAL DATA

ISSN:
1932-5150 (print)   1932-5134 (online)
Publisher:
AIP is a member of CrossRef SPIE

REFERENCES (16)

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