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Accuracy of cornea and lens biometry using anterior segment optical coherence tomography

J. Biomed. Opt., Vol. 12, 064023 (2007); doi:10.1117/1.2821844

Published 18 December 2007
Mark C. M. Dunne, Leon N. Davies, and James S. Wolffsohn
Aston University, Ophthalmic Research Group, Birmingham, United Kingdom
We assess the accuracy of the Visante anterior segment optical coherence tomographer (AS-OCT) and present improved formulas for measurement of surface curvature and axial separation. Measurements are made in physical model eyes. Accuracy is compared for measurements of corneal thickness (d1) and anterior chamber depth (d2) using-built-in AS-OCT software versus the improved scheme. The improved scheme enables measurements of lens thickness (d3) and surface curvature, in the form of conic sections specified by vertex radii and conic constants. These parameters are converted to surface coordinates for error analysis. The built-in AS-OCT software typically overestimates [mean±standard  deviation(SD)]d1 by +62±4  µm and d2 by +4±88µm. The improved scheme reduces d1 (−0.4±4  µm) and d2 (0±49  µm) errors while also reducing d3 errors from +218±90 (uncorrected) to +14±123  µm (corrected). Surface x coordinate errors gradually increase toward the periphery. Considering the central 6-mm zone of each surface, the x coordinate errors for anterior and posterior corneal surfaces reached +3±10 and 0±23  µm, respectively, with the improved scheme. Those of the anterior and posterior lens surfaces reached +2±22 and +11±71  µm, respectively. Our improved scheme reduced AS-OCT errors and could, therefore, enhance pre- and postoperative assessments of keratorefractive or cataract surgery, including measurement of accommodating intraocular lenses.

©2007 Society of Photo-Optical Instrumentation Engineers
History: Received 15 June 2007; revised 21 August 2007; accepted 22 August 2007; published 18 December 2007
DOI Link: http://dx.doi.org/10.1117/1.2821844
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KEYWORDS and PACS

Keywords
PACS
  • 42.66.Ct
    Anatomy and optics of eye
  • YEAR: 2007

JOURNAL DATA

ISSN:
1083-3668 (print)   1560-2281 (online)
Publisher:
AIP is a member of CrossRef SPIE

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