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Progress of near-infrared spectroscopy and topography for brain and muscle clinical applications
This review celebrates the 30th anniversary of the first in vivo near-infrared (NIR) spectroscopy (NIRS) publication, which was authored by Professor Frans Jöbsis. At first, NIRS was utilized to ...
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Functional near-infrared spectroscopy: current status and future prospects
Near-infrared spectroscopy (NIRS), which was originally designed for clinical monitoring of tissue oxygenation, has been developing into a useful tool for neuroimaging studies (functional near-infrare...

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Near-infrared spectroscopy/imaging for monitoring muscle oxygenation and oxidative metabolism in healthy and diseased humans

J. Biomed. Opt., Vol. 12, 062105 (2007); doi:10.1117/1.2805437

Published 16 November 2007
Takafumi Hamaoka
National Institute of Fitness and Sports, Department of Exercise Science, Shiromizu 1, Kanoya, 891-2393 Japan

Kevin K. McCully
University of Georgia, 115 Ramsey Center, 330 River Road, Athens, Georgia

Valentina Quaresima
University of L'Aquila, Department of Sciences and Biomedical Technologies, L'Aquila, 67100 Italy

Katsuyuki Yamamoto
Hokkaido University, Biomedical Systems Engineering Division of Bioengineering and Bioinformatics Graduate School of Information Science and Technology, North 14 West 9, Sapporo 060-0814, Japan

Britton Chance
University of Pennsylvania, Department of Biochemistry and Biophysics, Philadelphia, Pennsylvania 19104-6059
Near-infrared spectroscopy (NIRS) was initiated in 1977 by Jobsis as a simple, noninvasive method for measuring the presence of oxygen in muscle and other tissues in vivo. This review honoring Jobsis highlights the progress that has been made in developing and adapting NIRS and NIR imaging (NIRI) technologies for evaluating skeletal muscle O2 dynamics and oxidative energy metabolism. Development of NIRS/NIRI technologies has included novel approaches to quantification of the signal, as well as the addition of multiple source detector pairs for imaging. Adaptation of NIRS technology has focused on the validity and reliability of NIRS measurements. NIRS measurements have been extended to resting, ischemic, localized exercise, and whole body exercise conditions. In addition, NIRS technology has been applied to the study of a number of chronic health conditions, including patients with chronic heart failure, peripheral vascular disease, chronic obstructive pulmonary disease, varying muscle diseases, spinal cord injury, and renal failure. As NIRS technology continues to evolve, the study of skeletal muscle function with NIRS first illuminated by Jobsis continues to be bright.

©2007 Society of Photo-Optical Instrumentation Engineers
History: Received 1 May 2007; revised 6 July 2007; accepted 16 July 2007; published 16 November 2007
DOI Link: http://dx.doi.org/10.1117/1.2805437
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KEYWORDS and PACS

Keywords
PACS
  • 87.63.Lk
    Visible radiation: diaphanography, transillumination, laser imaging in medicine
  • 87.64.Je
    Infrared and Raman spectroscopy in biophysics and medical physics
  • 87.19.Ff
    Muscles
  • 87.15.Nn
    Properties of biomolecular solutions; aggregation and crystallization of macromolecules
  • 87.19.Xx
    Diseases
  • YEAR: 2007

JOURNAL DATA

ISSN:
1083-3668 (print)   1560-2281 (online)
Publisher:
AIP is a member of CrossRef SPIE

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