Variation of laser-induced retinal injury thresholds with retinal irradiated area: 0.1-s duration, 514-nm exposures
The retinal injury threshold dose for laser exposure varies as a function of the irradiated area on the retina. Zuclich reported thresholds for laser-induced retinal injury from 532 nm, nan...
Fiber optic biosensor for the detection of C-reactive protein and the study of protein binding kinetics
Application of a fiber optic biosensor (FOB) to the real-time investigation of the interaction kinetics between FITC-conjugated monoclonal sheep anti-human C-reactive protein (CRP) antibody and CRP is...
An optical fiber sensor formeasuring the pH in interstitial fluid is described. Microdialysis isthe approach followed for extracting the sample from the subcutaneousadipose tissue. The interstitial fluid drawn flows through a microfluidiccircuit formed by a microdialysis catheter in series with apH glass capillary. The pH indicator (phenol red) is covalentlyimmobilized on the internal wall of the glass capillary. Anoptoelectronic unit that makes use of LEDs and photodetectors isconnected to the sensing capillary by means of optical fibers.Optical fibers are used to connect the interrogating unit tothe sensing capillary. A resolution of 0.03 pH units andan accuracy of 0.07 pH units are obtained. Preliminary invivo tests are carried out in pigs with altered respiratoryfunction.
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