SPIE
Journal of Biomedical Optics Home PageJournal of Biomedical Optics Home Page
My SPIE Subscription | My E-mail Alerts | My Article Collections
 Search JBO
Advanced Search
 Browse JBO
Current Issue
Current Volume
All Volumes
 General Information
About the Journal
Citation Format
Subscriptions &
 Information
E-mail Alerts
Terms of Use
Institutions &
Corporations 
SPIEWeb
RSS icon RSS feed for the Journal of Biomedical Optics
Previous Article
Macular pigment Raman detector for clinical applications
Clinical studies of carotenoid macular pigments (MP) have been limited by the lack of noninvasive, objective instruments. We introduce a novel noninvasive optical instrument, an MP Raman detector, for...
Next Article
Calculation of ocular single-pass modulation transfer function and retinal image simulation from measurements of the polarized double-pass ocular point spread function
The single-pass modulation transfer function (MTFsgl) is an important numerical parameter that can help elucidate the performance and some processes of the human visual system. In previous studies, th...

You are not logged in to this journal. Log in

Three-dimensional computer-automated threshold Amsler grid test

J. Biomed. Opt., Vol. 9, 149 (2004); doi:10.1117/1.1625952

Online Publication Date: 7 January 2004
Wolfgang Fink
California Institute of Technology, Pasadena, California, and Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California

Alfredo A. Sadun
Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California
We describe a novel method for testing a visual field that employs a computer monitor with displays of varying contrast that permits unprecedented resolution and characterization of the structure of scotomas in three dimensions. Patients are placed in front of a touch-sensitive computer screen at a fixed distance. With one eye covered, they focus on a central fixation marker and trace with their finger the areas on an Amsler grid that are missing from their field of vision. Increasing degrees of contrast of the Amsler grid are simulated by repeating the test at different gray-scale levels. The results are recorded and then displayed as topographical contour rings by the computer test program. The results can also be rendered as an immediate 3-D depiction of the central hill-of-vision. Several clinical pilot studies have been conducted at the Doheny Eye Institute and more than 200 patients have been examined with this system so far. Conditions such as optic neuritis, anterior ischemic optic neuropathy (AION), age-related macular degeneration (AMD), glaucoma, and ocular hypertension have been successfully assessed by this test. Each condition provides unique patterns that are most evident in 3-D. The 3-D computer-automated threshold Amsler grid test is an innovative and noninvasive visual field test. It provides several advantages over state-of-the-art standard automated perimetry, including: (1) additional information through 3-D depiction of scotomas, such as location, extent, slope, depth, and shape; (2) high angular resolution (1 deg compared with typically 6 deg); (3) a simple test setup (merely a touch-sensitive computer monitor and the test software); (4) excellent patient compliance (spending 4 to 5 min per eye). In light of its promising initial tests, the 3-D visual field test appears to have the potential for the early detection and monitoring of various diseases over time.

©2004 Society of Photo-Optical Instrumentation Engineers.
History: Received Apr. 4, 2003; revised Jun. 30, 2003; accepted Jul. 1, 2003
DOI Link: http://dx.doi.org/10.1117/1.1625952
Buy This PDF  (US$25)
Download HTML Download Sectioned HTML Download PDF (691 kB) View Cart

KEYWORDS and PACS

Keywords
PACS
  • 87.63.Lk
    Visible radiation: diaphanography, transillumination, laser imaging in medicine
  • 42.66.Ct
    Anatomy and optics of eye
  • YEAR: 2004

JOURNAL DATA

ISSN:
1083-3668 (print)   1560-2281 (online)
Publisher:
AIP is a member of CrossRef SPIE

REFERENCES (21)

For access to fully linked references, you need to log in. For access to fully linked references, you need to Log in.

CITING ARTICLES


For access to citing articles, you need to log in.
For access to citing articles, you need to Log in.